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Severe thrombocytopenia in iron deficiency anemia

✍ Scribed by Mark Berger; Dr. Lawrence F. Brass

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 282 KB
Volume: 24
Category: Article
ISSN: 0361-8609
DOI: 10.1002/ajh.2830240412

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✦ Synopsis

Mild-to-moderate thrombocytopenia has been reported as an occasional finding in patients with iron deficiency. The present case describes a multiparous woman who presented with increased menorrhagia, severe anemia (3.0 g/dl) and thrombocytopenia (9,000 platelets/mm3). Her bone marrow examination showed iron deficiency, megakaryocytopenia, and erythroid hypoplasia but no other evidence of a primary marrow disorder. Her symptoms, the thrombocytopenia and the megakaryocytopenia, resolved with iron replacement. This case demonstrates the profound degree to which thrombopoiesis can be affected in iron deficiency.

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