Severe noninfectious acute lung injury in early phase of bone marrow transplantation
β Scribed by D. Gruson; G. Hilbert; F. Vargas; J. M. Boiron; A. Pigneux; J. Reiffers; G. Gbikpi-Benissan; J. P. Cardinaud
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 119 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1432-1238
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Between 1982 and 1986 51 patients were treated with ciclosporin a (CSA) to prevent graft versus host disease (GvHD) after bone marrow transplantation (BMT). Major side effects of the drug were tremor, hypertension, hepatotoxicity and nephrotoxicity. Acute GvHD 0 degree to II degree occurred in 80% o
Patients undergoing bone marrow transplantation are at high risk of developing acute graft-versus-host disease (GVHD) which is a primary limiting factor for this procedure inasmuch as it is responsible for high morbidity rates and is associated with poor survival outcome. To provide improved treatme