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Severe hypophosphatemia: A rare cause of intravascular hemolysis

✍ Scribed by Jennifer D. Melvin; Raymond G. Watts

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
46 KB
Volume
69
Category
Article
ISSN
0361-8609

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✦ Synopsis

Abstract

A 3‐year‐old child presented with severe hyperphosphatemia (phosphate 45 mg/dL) secondary to chronic enema use. Following aggressive correction of the hyperphosphatemia, hypophosphatemia ensued (phosphate 1.7 mg/dL). Concurrently, the patient developed severe intravascular hemolysis and RBC morphologic defects. The hemolysis and morphologic defects corrected with return to normal serum phosphate levels. Severe hypophosphatemia is a rare cause of intravascular hemolysis. Am. J. Hematol. 69:223–224, 2002. Β© 2002 Wiley‐Liss, Inc.

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In response to two case reports that have appeared in this journal [1,2], I would like to make the following comments: The authors state that there is no published report of hemolysis following coil embolization of the ductus arteriosus. This statement is factually incorrect. We have reported a cas