Severe hepatic injury in interleukin-18 transgenic mice
โ Scribed by Susetta Finotto; Raja Atreya; Manfred Blessing; Peter R. Galle; Markus F. Neurath
- Book ID
- 119425947
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 183 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0016-5085
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Hepatic ischemia/reperfusion injury is a clinically important problem. While the mechanisms of the initial event and subsequent neutrophil-dependent injury are somewhat understood, little is known about the regulation of endogenous hepatoprotective effects on this injury. Interleukin 12 (IL-12) play
Apoptosis appears to be a central mechanism of cell death following reperfusion of the ischemic liver. The aim of this study was to determine the effect of decreased expression of the proapoptotic Bax gene on hepatic apoptotic warm ischemia/reperfusion (I/R) injury. Three groups of mice were studied