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Severe growth defect in mouse cells lacking the telomerase RNA component

โœ Scribed by Niida, Hiroyuki; Matsumoto, Takehisa; Satoh, Hideo; Shiwa, Mieko; Tokutake, Yoshiki; Furuichi, Yasuhiro; Shinkai, Yoichi


Book ID
109826745
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
266 KB
Volume
19
Category
Article
ISSN
1061-4036

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Expression of the RNA component of human
โœ Ruby Delgado; Asha Rathi; Jorge Albores-Saavedra; Adi F. Gazdar ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 688 KB

## BACKGROUND. During human development, telomerase is repressed in most somatic cells, whereas it is maintained in male germline cells. Reactivation of telomerase has been associated with somatic cancers. To the authors' knowledge, the role of telomerase in germ cell derived malignancies has not