A 34-year-old man affected by exercise intolerance, mild proximal weakness and severe lactic acidosis is described. Muscle biopsy revealed mitochondrial abnormalities and an increase of cytochrome c oxidase histochemical reaction. Biochemical investigations on isolated muscle mitochondria as well as
β¦ LIBER β¦
Severe complex I deficiency in a case of neonatal-onset lactic acidosis and fatal liver failure
β Scribed by M Mazzella; R Cerone; W Bonacci; U Caruso; A Munnich; P Rustin; JM Saudubray; C Romano; G Serra
- Book ID
- 114811226
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 370 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0803-5253
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