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Severe combined immunodeficiency. A model disease for molecular immunology and therapy

✍ Scribed by Alain Fischer; Françoise Le Deist; Salima Hacein-Bey-Abina; Isabelle André-Schmutz; Geneviève De Saint Basile; Jean-Pierre De Villartay; Marina Cavazzana-Calvo

Book ID
110746578
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
836 KB
Volume
203
Category
Article
ISSN
0105-2896

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📜 SIMILAR VOLUMES

Severe combined immunodeficiency disease
Severe combined immunodeficiency disease, adenosine deaminase deficiency and gene therapy
✍ Robertson Parkman; Erwin W Gelfand 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 741 KB

Patients with severe combined immunodeficiency disease represent a model for the first clinical applications of gene therapy. Present attempts use insertion of the human adenosine deaminase gene into the peripheral blood T lymphocytes of patients who lack this gene. The ultimate treatment, however,