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Severe acute encephalopathy following inadvertent intrathecal doxorubicin administration

✍ Scribed by Aricó, Maurizio ;Nespoli, Luigi ;Porta, Fulvio ;Caselli, Dèsirèe ;Raiteri, Emanuela ;Burgio, G. Roberto

Book ID: 102520638
Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 203 KB
Volume: 18
Category: Article
ISSN: 0098-1532
DOI: 10.1002/mpo.2950180321

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✦ Synopsis

Abstract

In a female with acute lymphoblastic leukemia, inadvertent doxorubicin administration intrathecally caused severe, life‐threatening, acute encephalopathy with high‐pressure hydrocephalus. Ventriculoperitoneal shunting led to complete reversal of hydrocephalus with progressive disappearance of the acute encephalopathy.

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