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Several new approaches to improvement of alpha interferon therapy in chronic myelogenous leukaemia

✍ Scribed by Shigetaka Asano; Hiromi Ogura; Kenzaburo Tani; Tokiko Inoue; Arinobu Tojo; Keiya Ozawa

Book ID
119157056
Publisher
Elsevier Science
Year
1991
Weight
704 KB
Volume
27
Category
Article
ISSN
0277-5379

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Response to the combined administration
Response to the combined administration of interferons alpha and gamma after failure of single interferon therapy in chronic myelogenous leukaemia
✍ Kloke, Otto ;Becher, Reinhard ;Niederle, Norbert πŸ“‚ Article πŸ“… 1987 πŸ› Springer-Verlag βš– 332 KB

A previously untreated patient with benign phase chronic myelogenous leukaemia (CML) was treated with recombinant Interferon alpha-2b. Haematological remission was induced for a total of twelve months. Thereafter, the patient developed resistance to Interferon alpha manifested by an increase in leuc