No coin nor oath required. For personal study only.
Confirmation of the specificity of [ 18 F]-FEDAA1106 for PBR expressed in activated macrophages in the atherosclerotic plaque is a necessary prequel to evaluating the efficacy of this PET radioligand in a rabbit model of atheroma. The successful conclusion of these experiments will generate a powerful clinical tool for determining atheroma instability in man.
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## Introduction. Shell crosslinked nanoparticles (SCKs) are amphiphilic core-shell nanoparticles inspired from biological constructs (1-2). They are prepared by the self-assembly and subsequent crosslinking of block copolymer micelles and can be optimized for guest packaging. The easily controlled
## Abstract ## Objective Recently, genomeβwide association studies have identified 3 new susceptibility loci for Alzheimer's disease (AD), __CLU, CR1__, and __PICALM__. We leveraged available neuropsychological and autopsy data from 2 cohort studies to investigate whether these loci are associated
## Abstract Immunotherapeutic approaches are investigated for treatment of neurodegenerative diseases of the Alzheimer's dementia (AD) type. The identification of a Ξ²βamyloidβplaque specific epitope, AΞ²(4β10) (^4^FRHDSGY^10^), recognized by therapeutically active antibodies from transgenic AD mice