𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Session 10: Other


Publisher
John Wiley and Sons
Year
2005
Tongue
French
Weight
84 KB
Volume
48
Category
Article
ISSN
0022-2135

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✦ Synopsis


Expression of HER2/neu antigen in breast cancer has well-documented prognostic and predictive values. There are evidences that diagnostically important information may be obtained by detection of HER2 expression in other carcinomas e.g. prostate cancer. The use of molecular imaging of HER2 expression can help to avoid false-negative biopsy results associated with sampling errors of heterogeneity of an antigen expression. A number of conjugates based on anti-HER2 antibodies and their fragments has been proposed and evaluated for non-invasive imaging of HER2-expression in vivo.

The goal of this study was to evaluate a labeling of anti-HER2 Affibody molecule Z HER2:342 with 111


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