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Serum type III procollagen peptide concentrations in severe chronic active hepatitis: Relationship to cirrhosis and disease activity

✍ Scribed by Arthur J. McCullough; William N. Stassen; Russell H. Wiesner; Albert J. Czaja

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 666 KB
Volume: 7
Category: Article
ISSN: 0270-9139
DOI: 10.1002/hep.1840070112

No coin nor oath required. For personal study only.

✦ Synopsis

To analyze the correlations between the presence of cirrhosis and hepatocellular inflammation and the serum concentrations of the amino-terminal peptide of procollagen type 111 in chronic liver disease, we measured prodlagen type 1 1 1 concentrations in paired serum samples from 46 patients (17 had cirrhosis) with severe chronic active hepatitis during a therapeutic treatment trial. Coded sera were analyzed for procollagen type 111 concentrations using both a standard and a recently described Fab radioimmunoassay to compare their relative diagnostic accuracy.

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