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Serum soluble fas levels in ovarian cancer

✍ Scribed by Lukas Hefler; Klaus Mayerhofer; Alessandra Nardi; Alexander Reinthaller; Christian Kainz; Clemens Tempfer

Book ID
117189548
Publisher
Lippincott Williams and Wilkins
Year
2000
Tongue
English
Weight
198 KB
Volume
96
Category
Article
ISSN
0029-7844

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## Abstract Epithelial ovarian cancer (EOC) is treated mainly by platinum‐based combination chemotherapy. Chemotherapy induces apoptosis in which the Fas/Fas ligand pathway is important. Serum soluble Fas (sFas) is a biomarker of this pathway and functionally inhibits Fas‐/FasL‐mediated apoptosis.

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