## Abstract ## Objectives/Hypothesis: Serum protein profiling by SELDIβTOFβMS distinguishes pretreatment and postβtreatment samples from patients with head and neck squamous cell cancer (HNSCC) by disease status (diseaseβfree or recurrence) with a high degree of sensitivity and specificity. We sou
Serum, salivary and tissue proteomics for discovery of biomarkers for head and neck cancers
β Scribed by Drake, Richard R; Cazares, Lisa H; Semmes, O John; Wadsworth, J Trad
- Book ID
- 119992868
- Publisher
- Expert Reviews
- Year
- 2005
- Tongue
- English
- Weight
- 400 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1473-7159
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Squamous cell carcinoma of the head and neck (HNSCC) is the sixth most common cancer worldwide. Despite improvements in diagnosis and treatment, the five-year-survival rate of advanced HNSCC has only moderately increased, which is largely due to the high proportion of patients that present with adva
## Abstract Mass spectrometry (MS)βbased proteomics is a rapidly developing technology for both qualitative and quantitative analyses of proteins, and investigations into protein posttranslational modifications, subcellular localization, and interactions. Recent advancements in MS have made tremend