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Serum protein polymorphisms in a village community from the Gambia, West Africa (Hp, Tf, and Gc)

✍ Scribed by S. G. Welch; C. A. Swindlehurst; I. A. McGregor; K. Williams

Publisher: Springer
Year: 1979
Tongue: English
Weight: 240 KB
Volume: 48
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00273278

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✦ Synopsis

Serum samples from 857 inhabitants of the village of Keneba, The Gambia, West Africa, were examined by means of polyacrylamide gel electrophoresis. In 203 cases no haptoglobin could be detected, whilst in the remaining 654 samples the three common haptoglobin phenotypes were found with gene frequencies of 0.651 (Hp1) and 0.349 (Hp2). The D1 transferrin variant gene was found with a frequency of 0.025. In the serum Gc system the fast variant Gc-Ab was detected, the gene frequencies being: Gc1, 0.943; Gc2, 0.044; and GcAb, 0.013.

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