Renal clearance and protein binding of m
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Phillip A. Reece; Heather S. Hill; R. Malcolm Green; Raymond G. Morris; Barry M.
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Article
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1988
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Springer
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English
⚖ 426 KB
The renal clearance of melphalan and the fraction unbound in plasma were determined after intravenous infusion of 5 mg/m2 over 5 min in nine patients with cancer to obtain information regarding the mechanism of renal handling of melphalan. Four of the patients underwent bone marrow transplantation a