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Serum parathyroid hormone levels in patients with calcium pyrophosphate crystal deposition disease (chondrocalcinosis, pseudogout)

โœ Scribed by Paulding Phelps; Charles D. Hawker


Publisher
John Wiley and Sons
Year
1973
Tongue
English
Weight
447 KB
Volume
16
Category
Article
ISSN
0004-3591

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โœฆ Synopsis


Abstract

Immunoreactive parathyroid hormone was measured in the sera of 26 patients with calcium pyrophosphate crystal deposition disease, using a sensitive radioimmunoassay procedure. Elevated concentrations were found in the sera of 10 (38%) of these patients. Four of these 10 patients had hypercalcemia suggesting primary hyperparathyroidism, but 3 had hypocalcemia suggesting secondary hyperparathyroidism. The data extend the previously documented relationship between hyperparathyroidism and calcium pyrophosphate crystal deposition disease, but an explanation for the association is not readily apparent.


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โœ Lawrence M. Ryan; Michael P. Lynch; Daniel J. Mccarty ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 251 KB ๐Ÿ‘ 2 views

We measured the intracellular pyrophosphate level of platelets from patients with calcium pyrophosphate dihydrate deposition disease. Total and secretory granule pyrophosphates were in the same range in patients with chondrocalcinosis and in normal volunteers. Therefore, not all cells share in the e