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Serum p53 antibodies in small cell lung cancer: the lack of prognostic relevance

✍ Scribed by Jassem, Ewa; Bigda, Jacek; Dziadziuszko, Rafał; Schlichtholz, Beata; Le Roux, Delphine; Grodzki, Tomasz; Rzyman, Witold; Konopa, Krzysztof; Pobereżna, Marta; Dobrzańska, Zuzanna; Skokowski, Jan; Soussi, Thierry; Jassem, Jacek


Book ID
118569444
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
74 KB
Volume
31
Category
Article
ISSN
0169-5002

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Prognostic significance of serum p53 ant
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p53 tumour suppressor gene alterations are one of the most frequent genetic events in lung cancer. A subset of patients with p53 mutation and cancer exhibited circulating serum anti-p53 self-antibodies (p53-Ab). The prevalence of these antibodies in lung cancer is currently being analysed in a multi