Changes in the levels of DNA methylation
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Hongyan Zhu; Keyong Li; Jiren Liang; Jie Zhang; Qing Wu
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Article
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2011
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John Wiley and Sons
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English
⚖ 679 KB
## ABSTRACT To investigate the changes in the levels of DNA methylation in the testis during development after neonatal transient exposure to DNA methyltransferase (DNMT) inhibitors, we orally administered Sprague–Dawley (SD) rats with 5‐aza‐2′‐deoxycytidine (5‐aza‐CdR; 0.025 or 0.25 mg kg^−1^) or