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Serum levels of digoxin in sudden cardiac deaths

✍ Scribed by Eriksson, M. ;Lindquist, O. ;Edlund, B.

Publisher: Springer-Verlag
Year: 1984
Tongue: English
Weight: 212 KB
Volume: 93
Category: Article
ISSN: 1437-1596
DOI: 10.1007/bf00202981

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✦ Synopsis

Digoxin was determined in postmortem serum samples from 100 patients who died suddenly of cardiac disease. Twenty patients had digoxin levels below the therapeutic range. Twenty-one patients had normal values within the therapeutic range (1.2-2.5 nmol/l). In ten cases there was probably an overdosage. Another 15 patients had markedly elevated levels. No digoxin concentration was found (below 0.5 nmol/1) in 34 patients. The importance of determination of digoxin levels both by the clinician and the pathologist is stressed as well as the necessity of using a correct sampling technique at autopsy.

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