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Serum leptin in subjects with impaired glucose tolerance in relation to insulin sensitivity and first-phase insulin response

โœ Scribed by Turpeinen, A K; Haffner, S M; Louheranta, A M; Niskanen, L K; Miettinen, H; Uusitupa, M I J


Book ID
110043640
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
102 KB
Volume
21
Category
Article
ISSN
1476-5497

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Recent evidence suggests that the postprandial hyperglycaemia in impaired glucose tolerance is primarily due to impaired suppression of basal hepatic glucose output. This in turn appears to be secondary to decreased first phase insulin secretion, although decreased hepatic insulin sensitivity, which