Serum keratan sulfate levels in osteoarthritis patients
β Scribed by M. Barry E. Sweet; Angelina Coelho; Christine M. Schnitzler; Thomas J. Schnitzer; Mary Ellen Lenz; Itzhak Jakim; Klaus E. Kuettner; EUGENE J.-M. A. Thonar
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 440 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We have used an ELISA to quantify a highly sulfated epitope present on keratan sulfate, a carbohydrate chain found principally in cartilage proteoglycans. The serum level of the epitope provides an indirect measure of the rate of degradation of cartilage proteoglycans during normal turnover and can
Previous studies on chondrosarcoma proteoglycans have suggested that keratan sulfate content and average keratan sulfate chain length may be inversely related to the degree of cartilage tumor malignancy. The present study extended this work to an analysis of serum keratan sulfate in chondrosarcoma p