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Serum inhibitors of cellular immunity in human neuroblastoma. IgG subclass of blocking activity

✍ Scribed by David G. Jose; Frantisek Skvaril

Publisher
John Wiley and Sons
Year
1974
Tongue
French
Weight
397 KB
Volume
13
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

An autochthonous in vitro assay of cytotoxic cellular immunity against neuro‐blastoma cells was used to measure the specific blocking activity of serum from three children with untreated neuroblastoma. The blocking sera were fractionated into four IgG subclasses and blocking activity was found to be associated with IgG~1~ and IgG~3~, with lesser activity in IgG~4~ proteins.

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