Serum IgA immune response to individual rotavirus polypeptides in young children with rotavirus infection

Homotypic and heterotypic serum neutrali

Homotypic and heterotypic serum neutralizing antibody response to rotavirus proteins following natural primary infection and reinfection in children

✍ Gorrell, Rebecca J.; Bishop, Ruth F. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 149 KB

Worldwide trials of rotavirus vaccines are currently in progress, but the basis of cross-reactive immunity between rotavirus serotypes is yet to be elucidated. The involvement of the outer capsid proteins, VP7 and VP4, in the production of cross-reactive neutralizing antibody (N-Ab) is unclear, and