Recent animal studies show that endothelial cells in liver sinusoids are the main site for removal of sodium hyaluronate from the circulation. Few data with respect to hyaluronate metabolism are available in man. Serum hyaluronate levels were measured in 119 patients with liver disease by a sensitiv
Serum hyaluronate in liver diseases: Study by enzymoimmunological assay
✍ Scribed by Thierry Frébourg; Bertrand Delpech; Eric Bercoff; Professor Jacques Senant; Philippe Bertrand; Yves Deugnier; Jacques Bourreille
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 445 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0270-9139
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Abbreviations: HA, hyaluronic acid; PIIIP, aminoterminal propeptide of collagen type III; ROC, receiver operating characteristic. of entry into the study.
Primary biliary cirrhosis (PBC) is sometimes diagnosed based on a positive antimitochondrial antibody in the appropriate clinical setting without a liver biopsy. Although a liver biopsy can assess the extent of liver fibrosis and provide prognostic information, serum fibrosis markers avoid biopsy co
To study zonation of liver gene expression, we obtained periportal or perivenous rat liver cell lysates virtually devoid of nuclear material by site-directed digitonin infusion in situ. Total RNA was isolated, messenger RNAs were reverse transcribed and complementary DNAs were assayed after polymera