Serum HBV DNA as a marker of efficacy during therapy for chronic HBV infection: Analysis and review of the literature
โ Scribed by Herve; Mommeja-Marin; Elsa Mondou; M.Robert Blum; Franck Rousseau
- Book ID
- 111722235
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 148 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0270-9139
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Hepatitis B virus (HBV) and high liver iron deposits have both been associated with the development of cirrhosis. Among HBV factors, genotype and mutations in the basal core promoter (BCP) and precore regions have been most frequently studied but the evidence for a positive association with cirrhosi
## Abstract Hepatitis B virus (HBV) DNA was evaluated in peripheral blood mononuclear cells (PBMC) from 50 individuals utilising Southern hybridisation analysis. HBV DNA sequences were detected in PBMC from 16/29 (55 percent) of chronic hepatitis B virus (HBV) carriers with serum HBeAg and HBV DNA,