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Serum haptoglobin and C-reactive protein in human skeletal fluorosis

✍ Scribed by A.K. Susheela; P. Jethanandani

Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
756 KB
Volume
27
Category
Article
ISSN
0009-9120

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✦ Synopsis

Circulating levels of haptoglobin and C-reactive protein were studied in patients of skeletal fluorosis and compared with two types of controls. The first type of control included normal healthy individuals consuming water containing permissible levels of fluoride (up to 1 mg/L). The second type of control included individuals consuming water contaminated with fluoride (1.2-14.5 mg/L) but not exhibiting clinical manifestations of skeletal fluorosis. A significant increase in the levels of haptoglobin @ < 0.01) and C-reactive protein (p < 0.01) as well as a raised erythrocyte sedimentation rate were seen in patients of skeletal fluorosis as compared to both types of controls. The present study suggests the possibility of a subclinical inflammatory reaction occurring in patients with skeletal fluorosis.

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