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Serum-ferritin concentration and diagnostic59Fe2+absorption in humans with iron deficiency

✍ Scribed by H. C. Heinrich; E. E. Gabbe; J. Brüggemann

Publisher
Springer
Year
1977
Tongue
English
Weight
234 KB
Volume
64
Category
Article
ISSN
0028-1042

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Friedreich's ataxia (FRDA) is caused by point mutations or trinucleotide repeat expansions in both alleles of the gene encoding frataxin. Studies of frataxin homologues in lower eukaryotes suggest that mitochondrial iron accumulation may underlie the pathophysiology of FRDA. To evaluate the possible