Serum esterase genetics: Identification and hormone induction of theEs-1besterase in inbred rats

✍ Scribed by Kozo Matsumoto; Bunei Syuto; Yoh-Ichi Miyake; Akira Matsuhashi; Miki Aizawa

• Book ID: 104788874
• Publisher: Springer
• Year: 1979
• Tongue: English
• Weight: 427 KB
• Volume: 17
• Category: Article
• ISSN: 0006-2928
• DOI: 10.1007/bf00504349

✦ Synopsis

A previously unrecognized esterasefrom the sera of the appropriate strains of the rat Rattus norvegicus was revealed by a discontinuous polyacrylamide gel electrophoretic technique. This esterase migrated in the albumin region, whereas a previously known major albumin esterase controlled by the Es-2 locus migrated in the postalbumin region when the method was used. The new albumin esterase component which separated from the Es-2 esterase was identified as the product of the Es-lb gene. The new albumin esterase was not detectable in the sera of sexually mature males of the appropriate genotype, because the activity level of this esterase was influenced by sex hormones, especially androgen.