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Serum Enzymes in the Jaundiced Homozygous Gunn Rat

โœ Scribed by HARGREAVES, TOM; THOM, BARRY

Book ID
109638747
Publisher
Nature Publishing Group
Year
1964
Tongue
English
Weight
269 KB
Volume
204
Category
Article
ISSN
0028-0836

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The presence of a microsomal UDP-glucuro
The presence of a microsomal UDP-glucuronyl transferase for bilirubin in homozygous jaundiced gunn rats and in the crigler-najjar syndrome
โœ Gerard B. Odell; Julio O. Cukier; Glenn R. Gourley ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 962 KB

The infusion of a closely related derivative of bilirubin, its dimethyl diester (DME), into jaundiced (jj) Gunn rats was associated with biliary excretion of mono-and diglucuronides of bilirubin. In uitro incubation of DME with liver microsomes from jj rats demonstrated sequential demethylation and