Serum creatine kinase in the detection of duchenne muscular dystrophy carriers: Effects of season and multiple testing
β Scribed by Dr. Maire E. Percy; Dr. David F. Andrews; Dr. Margaret W. Thompson
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 634 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0148-639X
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## Abstract In the absence of an unambiguous test for identifying Duchenne muscular dystrophy (DMD) heterozygotes, methods are needed for combination of the results of individually equivocal tests as effectively and rationally as possible. We used logistic discrimination to assess the effectiveness
Carbonic anhydrase III (CAIII) and creatine kinase (CK) were measured in plasma samples from a series of females at-risk as carriers of Duchenne muscular dystrophy and compared with control groups. Both plasma CAIII and CK levels were raised in a proportion of carriers. Although measurement of CAIII