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Serum concentration of the pyridinoline crosslinked carboxyterminal telopeptide of type I collagen and urinary concentration of deoxypyridinoline as markers of bone metastases in human prostate carcinoma

✍ Scribed by Ken-ichiro Yoshida; Yoshikatsu Hosoya; Kyoko Arai; Shuhei Sumi; Mikihiko Honda


Book ID
115828492
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
155 KB
Volume
254
Category
Article
ISSN
0009-8981

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## Background: Bone scans, widely used for the detection of bone metastases from prostate carcinoma, can neither quantitate metastatic lesions nor detect osteolytic lesions. ## Methods: Serum concentrations of the carboxyterminal propeptide of type i procollagen (picp), the carboxyterminal pyridi

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## Objectives: We measured the levels of the pyridinoline crosslinked carboxyterminal telopeptide of type I collagen (ICTP) and osteocalcin (OC) in the serum of 12 rachitic and 27 healthy Nigerian children, and compared the performance of these relatively new markers of bone metabolism with establ

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BACKGROUND. We investigated whether a new marker of bone turnover, pyridinoline cross-linked carboxyterminal telopeptide of type I collagen (ICTP), could be useful in the assessment of bone metastasis and in monitoring of the response to treatment in patients with prostate cancer with bone metastasi