Serum complement level in patients with leukemia

✍ Scribed by Satoshi Yoshikawa; Kazumasa Yamada; Takato O. Yoshida

• Publisher: John Wiley and Sons
• Year: 1969
• Tongue: French
• Weight: 431 KB
• Volume: 4
• Category: Article
• ISSN: 0020-7136
• DOI: 10.1002/ijc.2910040613

✦ Synopsis

The serum complement level was studied in 94 cases of patients with myelogenous and lymphogenous leukemia, including long-term survivors. Studies on serial changes in the serum complement level at exacerbation stage and at remission stage in I0 patients with acute leukemia were carried out separately. In two cases of acute myelogenous leukemia, serum complement levels were followed up during the course of the clinical stage. Serum complement levels in the majority of cases of chronic leukemia patients studied remained within the range of healthy control complement levels, while wide variations were noted in acute leukemic patients, especially in those at the stage of exacerbation. In lymphogenous leukemic patients, complement levels showed a larger variation with a trend of either higher or lower values as compared to those of both healthy control subjects and myelogenous leukemia. The serum complement levels showed a tendency to fluctuate in accordance with the exacerbation and the remission of the disease, and in the majority of cases a normal serum complement level was seen at the stage of remission. Correlation between C'H,, values and C'I-Ajo values in patient sera was not found among the limited number of cases studied.