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Serum Cellular Apoptosis Susceptibility Protein for Cancer Diagnosis

✍ Scribed by Cheng-Jeng Tai; Chun-Chao Chang; Shing-Chuan Shen; Woan-Ruoh Lee; Ming-Chung Jiang

Book ID
119294146
Publisher
Elsevier
Year
2011
Tongue
English
Weight
283 KB
Volume
3
Category
Article
ISSN
1878-3317

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## Abstract Protein tyrosine phosphatase 1B (PTP1B) is a negative regulator of tyrosine kinase growth factor signaling. To assess the importance of PTP1B in the balance between death and survival in the liver, we have developed immortalized neonatal hepatocyte cell lines lacking (PTP1B^βˆ’/βˆ’^) or ove