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Serum Caffeine and Paraxanthine as Markers for Reported Caffeine Intake in Pregnancy

โœ Scribed by Mark A Klebanoff; MD; MPH; Richard J Levine; MD; MPH; Rebecca Dersimonian; ScD; John D Clemens; MD; Diana G Wilkins; PhD

Book ID
117704132
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
126 KB
Volume
8
Category
Article
ISSN
1047-2797

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Validation of a high-performance liquid
Validation of a high-performance liquid chromatography assay for quantification of caffeine and paraxanthine in human serum in the context of CYP1A2 phenotyping
โœ J. P. Koch; G. W. ten Tusscher; J. G. Koppe; H. J. Guchelaar ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 73 KB ๐Ÿ‘ 2 views

In this study the validation of a reversed-phase high-performance liquid chromatography (HPLC) method, with UVdetection, for both caffeine and paraxanthine in human serum is described. This method is feasible for cytochrome P450 1A2 (CYP1A2) phenotyping, according to the results of a pilot study. Wi