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Serum CA 125 concentrations in patients with benign ovarian tumours

✍ Scribed by Dr. Paul K. Buamah; Andrew W. Skillen

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
311 KB
Volume
56
Category
Article
ISSN
0022-4790

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✦ Synopsis

Serum CA 125 concentrations have been measured in 115 patients with histologically confirmed nonmalignant pelvic disease, that is, serous cystadenoma (n = 56), mucinous cystadenoma (n = 14), fibroma (n = 33), thecoma (n = 8), and Brenner tumour (n = 4). Increased CA 125 concentrations (>35 KU/L) were found in 14 patients, with a range of 4 6 8 9 1 KU/L, a mean of 205 KU/L, and a median of 97 KU/L. The highest values were found in patients with ascites. Serial measurements in one patient showed a fall in the 2 days immediately after surgery, over the next 3 days showing a two-to three-fold increase, followed by a slow return to normal over the next 7 weeks. Elevated CA 125 levels may not indicate ovarian malignancy and do not differentiate between benign and malignant pelvic masses.

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