✦ LIBER ✦
Serum autoantibody to the nucleolar antigen PM-Scl. Clinical and immunogenetic associations
✍ Scribed by Chester V. Oddis; Yutaka Okano; William A. Rudert; Massimo Trucco; Rene J. Duquesnoy; Thomas A. Medsger Jr.
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 647 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0004-3591
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✦ Synopsis
Objective. The inflammatory myopathies are characterized by distinctive autoantibodies that are associated with certain clinical features and immunogenetic patterns. Anti-PM-Scl is one such antibody and is found in pure myositis, myositis in overlap, and systemic sclerosis (SSc). Our purpose was to describe the clinical and immunogenetic associations of the anti-PM-Scl antibody.
Methods. Serum samples from 617 patients with various connective tissue diseases were screened for From the