Serum Antibodies to Peripheral Nerve Antigens in Guillain-Barré Syndrome
✍ Scribed by T. NEGISHI; T. YAMASHITA; K. NOMURA; T. HOSOKAWA; R. OHNO; K. HAMAGUCHI; K. UYEMURA
- Book ID
- 119861298
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 99 KB
- Volume
- 540
- Category
- Article
- ISSN
- 0890-6564
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Complement-king antibodies to peripheral nerve myelin (anti-PNM Ab) can be detected in the serum of patients with Guillain-Barre syndrome (GBS). Kinetics of these antibodies can be correlated with the changing clinical course; the appearance of activation products of the terminal complement cascade
Mixed haemagglutination and complement fixation tests were used to detect serum antibodies to peripheral nerve in 36 patients with acute Guillain-Barré syndrome. Twenty patients were treated with plasma exchange, 16 served as controls. A significant antibody titre was found in 19 patients with the h