Prenatal diagnosis and treatment of holo
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Le Phuc Thuy; John Belmont; William L. Nyhan
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Article
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1999
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John Wiley and Sons
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English
โ 157 KB
๐ 2 views
Holocarboxylase synthetase is one of two enzymes known to be involved in the metabolism of biotin. It catalyses the fixation of biotin to inactive apocarboxylases yielding active carboxylases. Deficiency of this enzyme leads to multiple carboxylase deficiency which is fatal in the absence of prompt