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Serum amyloid p component scintigraphy and turnover studies for diagnosis and quantitative monitoring of aa amyloidosis in juvenile rheumatoid arthritis

✍ Scribed by P. N. Hawkins; S. Richardson; D. M. Vigushin; J. David; C. R. Kelsey; R. E. S. Gray; M. A. Hall; P. Woo; J. P. Lavender; M. B. Pepys


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
925 KB
Volume
36
Category
Article
ISSN
0004-3591

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✦ Synopsis


To evaluate aspects of the natural history of AA amyloidosis complicating juvenile rheumatoid arthritis (JRA), and its response to therapy with chloram bucil.

Methods. Scintigraphy and 7-day turnover studies were performed in JRA patients with histologically proven (n = 35) or clinically suspected (n = 30) AA amyloidosis, following intravenous injection of 1231 and '25i-labeled serum amyloid P component (SAP). Pro-~