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Serum amyloid A (SAA) induces pentraxin 3 (PTX3) production in rheumatoid synoviocytes

✍ Scribed by Kenshi Satomura,Takafumi Torigoshi,Tomohiro Koga,Yumi Maeda…

Book ID
126348635
Publisher
Springer
Year
2012
Tongue
English
Weight
482 KB
Volume
23
Category
Article
ISSN
1439-7595

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The prototypic tissue pentraxin PTX3, in contrast to the short pentraxin serum amyloid P, inhibits phagocytosis of late apoptotic neutrophils by macrophages
✍ André P. van Rossum; Fausto Fazzini; Pieter C. Limburg; Angelo A. Manfredi; Patr 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 345 KB

## Abstract ## Objective Phagocytosis of apoptotic cells can be facilitated by complement components and short pentraxins, such as serum amyloid P (SAP). In contrast, the long pentraxin PTX3 was shown to inhibit phagocytosis of apoptotic Jurkat cells by dendritic cells and to bind late apoptotic p