Serum alphafetoprotein (AFP) in diagnosis and management of endodermal sinus (yolk sac) tumor and mixed germ cell tumor of the ovary
β Scribed by A. Talerman; W. G. Haije; L. Baggerman
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 533 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0008-543X
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The incidence of yolk sac tumor (endodermal sinus tumor) elements was studied in 147 germ cell neoplasms of the testis in adults observed over a 4 1/2-year period. Excluding 79 cases of pure seminoma, yolk sac tumor elements were found in 26 (38%) of 68 tumors; in 8 tumors the yolk sac tumor was the
The incidence of endodermal sinus tumor (EST) or yolk sac tumor (YST) elements has been studied in two series of testicular germ-cell neoplasms in adults. One series, consisting of 200 germ-cell neoplasms seen from 1953 through 1968, was studied retrospectively, and the other, consisting of 147 case
## Abstract Serum alphafoetoprotein (AFP) and serum alphaβ1 antitrypsin (AAT) were determined in 24 patients with germβcell neoplasms of the gonads and extragonadal sites and in two patients with hepatocellular carcinoma. In the majority of the patients serial determinations were performed. All sev
We report the cytogenetic findings in a case of mixed germ cell-sex cord-stromal tumor of the ovary in a 5-month-old girl. Monosomy 22 was observed as the sole karyotypic abnormality. This result was confirmed by comparative genomic hybridization, which revealed no additional chromosomal imbalances.
Primary alpha-fetoprotein secreting ovarian tumors have been detected in pregnancy by markedly elevated midtrimester MSAFP accompanied by sonographically visualized adnexal masses. We present a recurrent mixed germ cell tumor manifesting only as a moderately elevated MSAFP screen. A 23-year-old para