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Serrated Pathway to Colorectal Carcinogenesis: A Molecular Perspective

✍ Scribed by Ajay Goel; Francesc Balaguer


Book ID
107535791
Publisher
Current Science Inc.
Year
2011
Tongue
English
Weight
274 KB
Volume
7
Category
Article
ISSN
1556-3790

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## Abstract ## BACKGROUND A small proportion of patients with colorectal carcinoma (CRC) have synchronous tumors at the time of diagnosis. A subset of sporadic CRCs display microsatellite instability (MSI) that is associated with __MLH1__ silencing due to promoter methylation. In the current study