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Serotonin transporter gene polymorphism influences age at onset in patients with bipolar affective disorder

✍ Scribed by Frank Bellivier; Maÿliss Leroux; Chantal Henry; Fadila Rayah; Frédéric Rouillon; Jean-Louis Laplanche; Marion Leboyer


Book ID
117473258
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
79 KB
Volume
334
Category
Article
ISSN
0304-3940

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The serotonin transporter is a compelling candidate gene to examine in bipolar and unipolar affective disorder, since drugs that specifically inhibit the serotonin transporter can successfully treat depression. Previous association studies of a VNTR polymorphism in intron 2 and a functional insertio