Serotonin transporter gene polymorphism and affective disorder
β Scribed by H. Kunugi; M. Tatsumi; T. Sakai; M. Hattori; S. Nanko; G. Stober; A. Heils; K.P. Lesch
- Book ID
- 118561458
- Publisher
- The Lancet
- Year
- 1996
- Tongue
- English
- Weight
- 326 KB
- Volume
- 347
- Category
- Article
- ISSN
- 0140-6736
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The serotonin transporter is a compelling candidate gene to examine in bipolar and unipolar affective disorder, since drugs that specifically inhibit the serotonin transporter can successfully treat depression. Previous association studies of a VNTR polymorphism in intron 2 and a functional insertio
## Abstract Family, twin, and adoption studies show that psychiatric diseases including bipolar disorder (BP) and unipolar disorder (UP) have a substantial genetic component. For these illnesses, both positive and negative associations have been reported for two polymorphisms located in the seroton