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Serotonin transporter function and expression are reduced in mice with TNBS-induced colitis

โœ Scribed by D. R. Linden; K. F. Foley; C. Mcquoid; J. Simpson; K. A. Sharkey; G. M. Mawe


Book ID
110850552
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
237 KB
Volume
17
Category
Article
ISSN
1350-1925

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P-glycoprotein (P-gp), the product of the multiple drug resistance (mdr) gene, can actively pump toxic drugs out of cells, but its pathophysiologic role is not yet fully understood. In this study, we examined the expression of P-gp in dextran sodium sulfate (DSS)-induced colitis in mice. Eight-week-