Serotonin-stimulated intracellular calcium mobilization in platelets from alcoholic men
โ Scribed by Christopher Reist; Daiga Helmeste; Mark Katz; Ryan Vu; Lawrence Albers; Siu Wa Tang
- Book ID
- 119095931
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 351 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0165-1781
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Stimulation of human platelets with concanavalin A resulted in a significant increase in the concentration of c toplasmic free Ca2+. This effect was due to two different processes: Ca2+ mobilization from internal stores and Ca' influx from the extracellular medium. Kinetic analysis revealed that the
## Enhanced platelet functions have been reported in patients with diabetes mellitus. Our recent study demonstrated that phosphoinositide turnover is increased in platelets from diabetic patients. In the present study, we evaluated the abnormality in platelet intracellular calcium mobilization in