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Serotonin metabolism in the CNS in cerebellar ataxic mice

✍ Scribed by K. Ohsugi; K. Adachi; K. Ando

Publisher
Springer
Year
1986
Tongue
English
Weight
350 KB
Volume
42
Category
Article
ISSN
1420-682X

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## Abstract The effect of a lack of the gene encoding monoamine oxidase A (MAO A) in transgenic Tg8 mice on the activity of tryptophan hydroxylase (TPH), the rate‐limiting enzyme in serotonin (5‐HT) biosynthesis, and on the levels of 5‐HT and 5‐hydroxyindoleacetic acid (5‐HIAA) in the midbrain, hyp