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Serotonin levels are abnormally elevated in the fetus of the monoamine oxidase-A-deficient transgenic mouse

✍ Scribed by A.M Lajard; C Bou; R Monteau; G Hilaire


Book ID
117477387
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
64 KB
Volume
261
Category
Article
ISSN
0304-3940

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## Abstract The effect of a lack of the gene encoding monoamine oxidase A (MAO A) in transgenic Tg8 mice on the activity of tryptophan hydroxylase (TPH), the rate‐limiting enzyme in serotonin (5‐HT) biosynthesis, and on the levels of 5‐HT and 5‐hydroxyindoleacetic acid (5‐HIAA) in the midbrain, hyp