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Serotonin function in panic disorder: effect of 1–5-hydroxytryptophan in patients and controls

✍ Scribed by Herman G. M. Westenberg; Johan A. Boer

Publisher: Springer
Year: 1989
Tongue: English
Weight: 340 KB
Volume: 98
Category: Article
ISSN: 0033-3158
DOI: 10.1007/bf00444706

No coin nor oath required. For personal study only.

✦ Synopsis

The responsivity of the serotonergic system to 5-hydroxytryptophan (5-HTP) administration was investigated in seven patients with panic disorder and seven healthy controls. Using cortisol and fl-endorphin as hormonal probes, no evidence was obtained for a dysfunction of the serotonin system in patients. Behaviorally, controls responded differently from patients, in that controls seemed to be more sensitive to 5-HTP. None of the subjects reported an increase in anxiety.

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